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Brimstone - Overrides IPECAC, but the damage of the beam is tripled, with an increased charge time.

It turns into a good synergy with Pyromaniac, allowing for healing shots that boomerang back and health. Use on Rebirth as Challenge #7 Suicide King. This interaction is not advisable, as the shots fired will almost always come back at Isaac and deal explosive damage to him.

My Reflection: Causes the shots to come back toward Isaac.

The damage of the bombs is NOT increased, and no poison effect will apply. Fetus - Gives Bombs a green color, with a greatly decreased fire rate. If your movement speed gets too high, the trajectory becomes difficult to control and can even cause shots to hit you while moving backward and firing forwards at the same time.Items that increase your range stat are not recommended with IPECAC, as they can make it harder to aim your shots.Firing directly in front of an obstacle or an enemy is not recommended, as the shots will instantly explode at point-blank and deal damage to Isaac.This item is excellent for finding the Secret Room or the Super Secret Room, due to its infinite explosive potential.However, IPECAC shots can hit like normal tears before exploding, which only deals normal tear damage. IPECAC shots are fired in an arc, making enemies difficult to hit without a proper Range stat.Įach IPECAC shot does normal tear damage + 50 (+40 since Rebirth) to any enemies in the explosion radius. Its poison deals 7 damage per tick.

A bottle of medicated syrup, with a label that reads "IPECAC" with a red warning label below.Īllows Isaac to fire projectiles from his mouth, causing explosive/ poison damage.